How to diagnose a benign spindle cell tumor?

How to diagnose a benign spindle cell tumor?

The recognition of the benign spindle cell tumor-like lesions (nodular fasciitis; reactive spindle cell nodule after biopsy, inflammatory pseudotumor/inflamma … Differential Diagnosis of Benign Spindle Cell Lesions Surg Pathol Clin. 2018 Mar;11(1):91-121.doi: 10.1016/j.path

What kind of cancer is a spindle cell lesion?

A spindle cell lesion ( MPNST ). H&E stain. Spindle cell lesions are seen frequent enough that one ought to have a solid approach to ’em. A general introduction to spindle cells is found in the spindle cell article. Nerve. Muscle. Smooth. Skeletal. Other. Carcinoma, e.g. metaplastic carcinoma. Monomorphic – small variation of tumour cell size.

Where are the spindle cell lesions located in the Git?

Noting whether a tumor is centered in the mucosa, submucosa, muscularis propria, or serosa goes a long way toward establishing a differential diagnosis; each type of lesion is often restricted to one of these layers. Table 1 shows the likely locations of various GIT mesenchymal lesions.

How are spindle cell tumors of the pleura diagnosed?

Here, we review morphological, clinical, histological, immunohistochemical, ultrastructural, and molecular methods that aid in the diagnosis of spindle cell tumors of the pleura, and we provide specific examples of patients in which this multi-modal approach proved to be helpful. Research Support, N.I.H., Extramural

When to use differential diagnosis for spindle cell sarcoma?

Differential diagnosis are also performed if the diagnostic tests revealed that the patient is negative for spindle cell sarcoma. A number of health conditions with identical symptoms with spindle cell sarcoma are osteolytic osteosarcoma, metastatic carcinoma, and aneurysmal bone cyst.

A spindle cell lesion ( MPNST ). H&E stain. Spindle cell lesions are seen frequent enough that one ought to have a solid approach to ’em. A general introduction to spindle cells is found in the spindle cell article. Nerve. Muscle. Smooth. Skeletal. Other. Carcinoma, e.g. metaplastic carcinoma. Monomorphic – small variation of tumour cell size.

What can you do about a spindle cell tumor?

•Refresh and broaden your knowledge of spindle cell lesions •Help you to establish a histology based approach for classification of spindle cell tumors •Learn distinctive features of select spindle cell tumors for accurate identification So you have a spindle cell lesion…now what?

Which is positive for S100 in spindle cell melanoma?

In spindle cell squamous cell carcinoma, squamous differentiation and cytokeratin expression are present. Spindle cell melanoma is positive for S100 protein, whereas AFX is entirely negative.