How long can you take phenylpropanolamine?
Although the risk of hemorrhagic stroke is low, the U.S. Food and Drug Administration (FDA) recommends that consumers not use any products that contain phenylpropanolamine. Do not take phenylpropanolamine for longer than 7 days if your condition does not improve or if your symptoms are accompanied by a high fever.
Do you need a prescription for phenylpropanolamine?
It is available in nonprescription products alone and in combination with other nonprescription drugs, to treat symptoms of allergy , colds, and upper respiratory infections. Phenylpropanolamine is also used as an adjunct to calorie restriction in short-term weight loss.
How safe is PROIN for dogs?
IMPORTANT SAFETY INFORMATION: In some cases, death, including euthanasia, has been reported. Sudden death was sometimes preceded by vocalization or collapse. Instances of dogs chewing through closed vials of PROIN® and eating the vial contents have been reported, in some cases resulting in overdose.
What does phenylpropanolamine do to a dog?
Phenylpropanolamine for dogs is a drug that is often prescribed for urinary incontinence. It increases the strength of the muscles in the bladder and the urethra, which in turn prevents the leakage of urine. The use of phenylpropanolamine has some known side effects and complications that dog owners should discuss with their veterinarian.
Are there any analogues of phenylpropanolamine?
Pharmaceutical drug preparations of PPA have varied in their stereoisomer composition in different countries, which may explain differences in misuse and side effect profiles. Analogues of PPA include ephedrine, pseudoephedrine, amphetamine, methamphetamine, and cathinone.
What is the half life of phenylpropanolamine?
Its hydrochloride salt is freely soluble in water and well-absorbed in the GI tract with over 60% bioavailability. It also exhibits linear pharmacokinetics in the dose range 25–100 mg with a plasma half-life of 2–3 hours.
How many mg of phenylpropanolamine does a normal person take?
Phenylpropanolamine (Norephedrine, Propadrine), an adrenergic vasoconstrictor, appears to have little or no effect on the pupils in normal people when given in ordinary doses of 25 to 50 mg of the hydrochloride salt.
Phenylpropanolamine for dogs is a drug that is often prescribed for urinary incontinence. It increases the strength of the muscles in the bladder and the urethra, which in turn prevents the leakage of urine. The use of phenylpropanolamine has some known side effects and complications that dog owners should discuss with their veterinarian.
How long does it take for phenylpropanolamine to work?
You should expect to give several days worth of doses before you see any improvement in your dog’s condition. Be sure to investigate the actual cause of incontinence in your dog before relying on a drug such as phenylpropanolamine to suppress symptoms.
When is the best time to give my dog phenylpropanolamine?
Provide access to fresh water at all times. If incontinence occurs at night, give the largest dose at night, before going to sleep. This medication will take effect quickly, in about 1 to 2 hours, and improvement in clinical signs should follow. What if I miss giving my pet the medication?
Why was phenylpropanolamine banned in the US?
Phenylpropanolamine, or PPA, was previously used as a decongestant for humans but was banned in the United States in 2000 because of evidence it caused risk of stroke in women. However, many veterinarians still prescribe PPA to help with urinary incontinence in dogs.