Is it safe to take DHEA for 6 months?

Is it safe to take DHEA for 6 months?

These findings led us to assess the effect of a larger dose (100 mg) of DHEA for a longer duration (6 months) on circulating sex steroids, body composition (DEXA) and muscle strength (MedX).

What was the design of the DHEA study?

Subjects and design: Healthy non-obese age-advanced (50-65 yrs of age) men (n = 9) and women (n = 10) were randomized into a double-blind placebo-controlled cross-over trial. Sixteen subjects completed the one-year study of six months of placebo and six months of 100 mg oral DHEA daily.

What is the effect of DHEA on SHBG levels?

Basal SHBG levels were in the normal range for men and elevated in women, of whom 7 of 8 were on oestrogen replacement therapy. While on DHEA, serum SHBG levels declined with a greater (P < 0.02) response in women (-40 +/- 8%; P = 0.002) than in men (-5 +/- 4%; P = 0.02).

Where are DHEA and DHEA sulphate precursors found?

1 Department of Reproductive Medicine, School of Medicine, University of California San Diego, La Jolla, USA. Objective: The biological role of the adrenal sex steroid precursors–DHEA and DHEA sulphate (DS) and their decline with ageing remains undefined.

What are the effects of DHEA for 6 months?

No significant adverse effects were observed. Conclusions: A daily oral 100 mg dose of DHEA for 6 months resulted in elevation of circulating DHEA and DS concentrations and the DS/cortisol ratio. Biotransformation to potent androgens near and slightly above the range of their younger counterparts occurred in women with no detectable change in men.

How much DHEA can you take in a day?

Recommended Doses. For adult males above the age of 19, the recommended daily dosage of DHEA is 50 mg, according to the University of Maryland Medical Center. For females above the age of 19, the recommended daily dosage is 25 mg.

Where does DHEA come from in the body?

DHEA helps to make other hormones, like testosterone in men and estrogen in women. Your natural DHEA levels are highest when you’re a young adult. They get lower as you age. In your adrenal glands and liver, DHEA changes to DHEA-S (DHEA-sulfate).

When is the best time to take a DHEA test?

If you’re a woman, your doctor may do the test a week before or after your period. That’s because menstruation affects your DHEA levels. A lab worker will take a blood sample from your arm with a needle. The normal range for DHEA-S depends on your age, sex, health, and even the way the lab measures the results.