What are the withdrawal symptoms of metoprolol tartrate?
Withdrawal symptoms, including headache, diaphoresis, palpitations, sinus tachycardia, tremor, and hypertension, have been associated with abrupt discontinuation of beta-blockers in hypertensive patients.
Can you abruptly stop metoprolol tartrate?
FDA warning: Don’t stop taking metoprolol suddenly Don’t stop taking metoprolol suddenly. If you do, you may experience worse chest pain, a jump in blood pressure, or even have a heart attack. Stopping metoprolol is not recommended. If you need to stop taking the drug, first talk to your doctor.
Can metoprolol tartrate 50 mg be crushed?
Metoprolol should be taken with a meal or just after a meal. Take the medicine at the same time each day. Swallow the capsule whole and do not crush, chew, break, or open it.
How long does metoprolol tartrate stay in your system?
The mean elimination half-life of metoprolol is 3 to 4 hours; in poor CYP2D6 metabolizers the half-life may be 7 to 9 hours. Approximately 95% of the dose can be recovered in urine. In most subjects (extensive metabolizers), less than 10% of an intravenous dose are excreted as unchanged drug in the urine.
What to expect when you stop taking metoprolol?
WARNING: Do not stop taking this medication without consulting your doctor. Some conditions may become worse when you suddenly stop this drug. Some people who have suddenly stopped taking similar drugs have had chest pain, heart attack, and irregular heartbeat.
Do you have to taper off metoprolol?
Avoid abrupt discontinuation. Stopping metoprolol (both tartrate and succinate) suddenly can exacerbate angina and may increase the risk of a heart attack. Reduce dosage gradually over a few weeks as instructed by your doctor.
Is 50 mg of metoprolol a lot?
The dose is usually 1 milligram (mg) per kilogram (kg) of body weight per day, given as a single dose. The first dose should not be more than 50 mg per day.
What happens if you crush metoprolol?
Do not crush or chew extended-release tablets or capsules. Doing so can release all of the drug at once, increasing the risk of side effects.