What are the symptoms of high alkaline phosphatase levels?
In most cases, higher levels of alkaline phosphates are closely associated with bone disorders, liver damage, liver disease, or a blocked bile duct. High alkaline phosphatase symptoms include fatigue and weakness, nausea and vomiting, weight loss, fever, itching, yellow skin, dark urine, abdominal pain, and many more.
What causes a high Alk Phos in the liver?
A high alk phos level does not reflect liver damage or inflammation. A high alk phos level occurs when there is a blockage of flow in the biliary tract or a buildup of pressure in the liver–often caused by a gallstone or scarring in the bile ducts.
What does elevated ALP mean in a blood test?
A blood test for ALP is done to diagnose a number of conditions of the liver and bones, as well as a few other conditions. Elevated levels of ALP may indicate damage to the liver, obstructed bile ducts, various bone disorders including rickets, Paget’s disease, osteomalacia, bone cancer and other tumors in the bones.
What causes elevated alkaline phosphatase in the placenta?
What Causes Elevated Alkaline Phosphatase? Pregnancy- The placenta, at the beginning of the third trimester, produces high levels of alkaline phosphatase enzymes. It tends to increase the maternal values beyond their normal range. The increase is important in the synthesis of proteins, calcification of the cartilage, and the bones.
What is an elevated ALP level indicative of?
Abnormal ALP levels indicate that a person may have gallstones . As ALP is most abundant in the bones and liver, elevated ALP levels are generally a sign of a liver or bone condition . An obstruction of the liver or damage to it will cause ALP levels to rise.
What medications can make alkaline phosphatase high?
Many common over-the-counter and prescription drugs can elevate alkaline phosphatase levels. For example, hypertension drugs such as propanolol or verapamil or gout treatments such as allopurinol can raise levels.
What does having an elevated AST/SGOT indicate?
Moderately elevated SGOT levels can suggest damage to the liver or other tissues as in alcoholics. Very high levels of SGOT can be found in recent liver injury or infection involving the liver. SGOT levels tend to be higher than SGPT in non-hepatic conditions such as shock and congestive heart failure.
What causes elevated level of alkaline phosphate?
Gastrointestinal Disease. Alkaline phosphatase is released into the blood in some diseases of the gastrointestinal tract, according to “Harrison’s Principles of Internal Medicine.” It is found in the biliary system which is responsible for taking bile from the liver to the intestines to aid in digestion. Diseases of the…