Are spindle cell tumors always cancerous?

Are spindle cell tumors always cancerous?

Tumours made up of spindle cells These tumours can be either benign (non-cancerous) or malignant (cancerous). The type of tumour depends on the location in the body and the way the cells look when examined under the microscope. Most cancers made up of spindle cells are called sarcomas.

What is undifferentiated spindle cell sarcoma?

Undifferentiated pleomorphic sarcoma (UPS), which is also referred to as malignant fibrous histiocytoma (MFH) according to the 2002 World Health Organization classification, is a rare and aggressive type of mesenchymal malignancy with no definitive cell of origin or specific recurrent genetic hallmarks.

How fast does undifferentiated pleomorphic sarcoma grow?

Sarcomas are very rare soft tissue neoplasms, but they should not be excluded as a differential when a patient presents with an enlarging mass, especially if the mass is located in the extremities, retroperitoneum, or head and neck. Sarcomas enlarge rapidly, in this case growing 24×9.5×7 cm in only 9 months.

Is undifferentiated pleomorphic sarcoma curable?

Summary. MFH is a curable disease. The term “Malignant Fibrous Histiocytoma” has been changed by the WHO to Undifferentiated Pleomorphic Sarcoma Not Otherwise Specified. The mainstays of treatment for MFH are complete surgical excision most often supplemented with adjuvant radiation therapy.

Can Tumors be long and skinny?

Dermatofibrosarcoma protuberans, also called DFSP, is a slow growing tumor consisting of long, narrow cells with tapered ends. Because of their appearance, doctors call them spindle cells. These tumors form in the skin or just below it, and surgery can lead to a remission.

Is Stage 4 a sarcoma terminal?

Stage IV soft tissue sarcoma A sarcoma is considered stage IV when it has spread to distant parts of the body. Stage IV sarcomas are rarely curable. But some patients may be cured if the main (primary) tumor and all of the areas of cancer spread (metastases) can be removed by surgery.

How are spindle cell tumors treated?

The usual treatment for spindle cell sarcoma is surgery to remove the tumour. Chemotherapy can be used in certain situations and we will discuss this with you we feel this is a suitable option.

What is the survival rate of spindle cell sarcoma?

Survival rates decreased with increasing age. The relative 5-year survival rates were 84% for those aged 20 to 49 years and 48% for those 50 to 69 years. Those older than 70 years had a 2-year relative survival rate of only 30%.

Does spindle cell carcinoma spread?

As with all cancers, spindle cell sarcoma can spread (metastasise) to other parts of the body.

What kind of cancer is a spindle cell tumor?

Spindle cell sarcoma is a type of connective tissue cancer in which the cells are spindle-shaped when examined under a microscope. The tumors generally begin in layers of connective tissue such as that under the skin, between muscles, and surrounding organs, and will generally start as a small lump with inflammation that grows.

When to use differential diagnosis for spindle cell sarcoma?

Differential diagnosis are also performed if the diagnostic tests revealed that the patient is negative for spindle cell sarcoma. A number of health conditions with identical symptoms with spindle cell sarcoma are osteolytic osteosarcoma, metastatic carcinoma, and aneurysmal bone cyst.

Why does spindle cell sarcoma have high cellular turnover?

In response to an injury, infection, or other immune response the connective tissues will begin dividing to heal the affected area, and if the tissue is predisposed to spindle cell cancer the high cellular turnover may result in a few becoming cancerous and forming a tumor. Wikimedia Commons has media related to Spindle cell sarcoma.

How old do you have to be to have spindle cell cancer?

They will undergo cell division, which increases the risk of cancer. Another possible cause of spindle cell sarcoma is direct contact with carcinogenic chemicals. Anyone can have a spindle cell carcinoma, but it is more prevalent in people 40 years old and above.

Spindle cell sarcoma is a type of connective tissue cancer in which the cells are spindle-shaped when examined under a microscope. The tumors generally begin in layers of connective tissue such as that under the skin, between muscles, and surrounding organs, and will generally start as a small lump with inflammation that grows.

What are soft tissues affected by spindle cell sarcoma?

The soft tissues like muscle, fat, fibrous tissues, nerves, deep skin tissues or blood vessels, which are seems as spindle shaped means long, narrow appearance under microscope, affected by sarcoma called spindle cell sarcoma.

What kind of soft tissue cancer is undifferentiated?

Undifferentiated pleomorphic sarcoma (UPS), formerly referred to as malignant fibrous histiocytoma, is a type of soft tissue cancer.

What are the soft tissues that are spindle shaped?

The soft tissues like muscle, fat, fibrous tissues, nerves, deep skin tissues or blood vessels, which are seems as spindle shaped means long, narrow appearance under microscope, affected by sarcoma called spindle cell sarcoma. (1)