What happens if you chew duloxetine?

What happens if you chew duloxetine?

Cymbalta is a delayed-release product. Swallow Cymbalta capsules whole, do not crush or chew. Do not open the capsule and sprinkle on foods or liquids, because this may affect the way the contents of the capsule are absorbed.

Is 30 mg of Cymbalta a lot?

Adults—40 milligrams (mg) per day (given as 20 mg two times per day) to 60 mg per day (given either once a day or as 30 mg two times per day). Your doctor may increase your dose as needed. However, the dose is usually not more than 120 mg per day.

What is duloxetine 30mg side effects?

Nausea, dry mouth, constipation, loss of appetite, tiredness, drowsiness, or increased sweating may occur. If any of these effects persist or worsen, tell your doctor promptly. Dizziness or lightheadedness may occur, especially when you first start or increase your dose of this drug.

What is duloxetine 30mg used for?

Duloxetine is used to treat depression and anxiety. It is also used for pain caused by nerve damage associated with diabetes (diabetic peripheral neuropathy). Duloxetine is also used to treat fibromyalgia (muscle pain and stiffness) and chronic (long-lasting) pain that is related to muscles and bones.

Is 30 mg of Cymbalta effective?

For some patients, it may be desirable to start at 30 mg once daily for 1 week, to allow patients to adjust to CYMBALTA before increasing to 60 mg once daily. While a 120 mg/day dose was shown to be effective, there is no evidence that doses greater than 60 mg/day confer any additional benefits.

Is Cymbalta 30 mg effective?

Conclusions: Results from this open-label study in patients with MDD suggest that starting duloxetine treatment at 30 mg QD for 1 week, followed by escalation to 60 mg QD, might reduce the risk for treatment-emergent nausea in these patients while producing only a transitory impact on effectiveness compared with a …

Is duloxetine a strong antidepressant?

Duloxetine is an antidepressant medicine. It’s used to treat depression and anxiety. It’s also used to treat nerve pain, such as fibromyalgia, and can be used to treat stress urinary incontinence in women. Duloxetine comes as capsules and is only available on prescription.

Is it better to take duloxetine in the morning or at night?

It is best to take duloxetine at the same time each day. Most people take it in the morning. If you find that you feel drowsy after taking it in the morning, try taking it in the evening. Important Duloxetine may cause drowsiness.

Is Cymbalta 30 mg effective for anxiety?

Duloxetine is a serotonin-norepinephrine reuptake inhibitor (SNRI) which is FDA approved for the treatment of generalized anxiety disorder (GAD) in doses of 30 mg to 120 mg daily.

How many milligrams of Cymbalta should a 7 year old take?

Safety of doses above 120 mg once daily has not been adequately evaluated [see Clinical Studies]. Children And Adolescents (7 To 17 Years Of Age) Initiate CYMBALTA at a dose of 30 mg once daily for 2 weeks before considering an increase to 60 mg. The recommended dose range is 30 to 60 mg once daily.

How many milligrams of Cymbalta are in breast milk?

The women were given 40 mg of CYMBALTA twice daily for 3.5 days. The peak concentration measured in breast milk occurred at a median of 3 hours after the dose. The amount of CYMBALTA in breast milk was approximately 7 mcg/day while on that dose; the estimated daily infant dose was approximately 2 mcg/kg/day.

How often should I take Cymbalta for fibromyalgia?

The recommended starting CYMBALTA dosage in pediatric patients 13-17 years of age with fibromyalgia is 30 mg once daily. The dosage may be increased to 60 mg once daily based on response and tolerability. The recommended CYMBALTA dosage is 60 mg once daily in adults with chronic musculoskeletal pain.

When to increase the dose of Cymbalta in the elderly?

Elderly Initiate CYMBALTA at a dose of 30 mg once daily for 2 weeks before considering an increase to the target dose of 60 mg. Thereafter, patients may benefit from doses above 60 mg once daily. If a decision is made to increase the dose beyond 60 mg once daily, increase dose in increments of 30 mg once daily.

How many mg of Cymbalta should a 7 year old take?

Safety of doses above 120 mg once daily has not been adequately evaluated [see Clinical Studies ( 14.2 )]. Children and Adolescents (7 to 17 years of age) — Initiate CYMBALTA at a dose of 30 mg once daily for 2 weeks before considering an increase to 60 mg. The recommended dose range is 30 to 60 mg once daily.

How long does it take for Cymbalta to work for anxiety?

After dealing with it over a year, I started generic Cymbalta 3 months ago. First 2 months 30 mg a day. Some initial insomnia, 1 day of upset stomach, loss of appetite (lost 8 lbs) for about 3 weeks. Helped immediately with depression, anxiety issues took about 5 weeks.

Elderly-Initiate CYMBALTA at a dose of 30 mg once daily for 2 weeks before considering an increase to the target dose of 60 mg. Thereafter, patients may benefit from doses above 60 mg once daily. If a decision is made to increase the dose beyond 60 mg once daily, increase dose in increments of 30 mg once daily.

Can you take Cymbalta hydrochloride more than once daily?

While a 120 mg once daily dose was shown to be effective, there is no evidence that doses greater than 60 mg/day confer additional benefit. Nevertheless, if a decision is made to increase the dose beyond 60 mg once daily, increase dose in increments of 30 mg once daily. The safety of doses above 120 mg once daily has not been adequately evaluated.