Can you overdose a dog on zonisamide?
If my pet gets too much of this medication (an overdose), what should I do? One-time overdoses of zonisamide may cause serious effects on the heart and lungs (eg, slow heart rate and breathing). If you witness or suspect an overdose, contact your veterinarian or an animal poison control center for further advice.
How long does it take a dog to adjust to zonisamide?
1) Many pets will act sleepy or drunk while their body adjust to the medication. It can take two weeks for some pets to adjust.
How long do the side effects of zonisamide last in dogs?
The effects of this short-acting medication typically last only 24 hours in dogs. In cats, it can last for approximately 48 hours, and therefore side effects may last for 1-2 days even after this medication is discontinued.
Can zonisamide cause liver damage in dogs?
In this case, continuous administration of zonisamide is considered as a main cause of the liver injury. In the limited cases of zonisamide-induced acute liver injury in dogs, anorexia, vomiting [3, 4] and a marked increase in liver enzyme levels (ALT, AST and ALP) [3] were reported as clinical features.
Will zonisamide hurt my dog?
Liver injury is possible and dogs should be monitored during treatment. Zonisamide is a sulfonamide drug, and dogs sensitive to sulfonamides may be at higher risk for reactions to zonisamide. Adverse reactions can include lethargy, ataxia, and vomiting.
Can you give a full capsule of zonisamide to a dog?
It is recommended to give a full capsule and breaking the capsule is not at all recommended. Always make sure your pet dog has enough water while it takes the Zonisamide capsule. Zonisamide capsules should be stored at room temperature. Moreover, keep the medicine out of the reach of children, other pets and direct light.
Can you take zonisamide in combination with potassium bromide?
Ways to Take Zonisamide. Zonisamide can be used by itself or combined with other anticonvulsant medications. For dogs that cannot tolerate Phenobarbital or potassium bromide, Zonisamide may be a viable option. It may also be an option for dog owners who do not want to risk the side effects of Phenobarbital or potassium bromide for their dog.
What are the side effects of Zonegran for dogs?
Uses of zonisamide for dogs. Zonegran (zonisamide) is an anti-convulsant found to be effective in the treatment of: Side effects of zonisamide use in dogs. The most common side effects include loss of coordination, sedation, vomiting and loss of appetite.
Can a dog take phenobarbital with potassium bromide?
For pets that cannot tolerate these drugs, or for pet owners who do not want to risk the side effects, Zonisamide may be a viable option. 2 Pets receiving phenobarbital or potassium bromide must also have blood levels of these drugs measured to ensure they are receiving the appropriate dose.
Is there an alternative to zonisamide for dogs?
This is useful when your pet’s seizures are inadequately controlled with those drugs. Zonisamide is also an alternative for animals that are allergic to, or have serious side effects from, other anti-seizure medications. Zonisamide can be used by itself or combined with other anticonvulsant medications.
Ways to Take Zonisamide. Zonisamide can be used by itself or combined with other anticonvulsant medications. For dogs that cannot tolerate Phenobarbital or potassium bromide, Zonisamide may be a viable option. It may also be an option for dog owners who do not want to risk the side effects of Phenobarbital or potassium bromide for their dog.
Uses of zonisamide for dogs. Zonegran (zonisamide) is an anti-convulsant found to be effective in the treatment of: Side effects of zonisamide use in dogs. The most common side effects include loss of coordination, sedation, vomiting and loss of appetite.
What’s the half life of zonisamide in dogs?
Zonisamide is metabolized by hepatic microsomal enzymes. h In dogs, the half-life is “15 hours, with steady state reached in 3 to 4 days.4,5 h In cats, the half-life is “33 hours, with steady state expected in “1 week.6 PROTOCOL In dogs, a starting dosage of !-” mg/kg PO q#$h is recommended.#,$